| State Road 143 | ||||
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| Route information | ||||
| Maintained by FDOT | ||||
| Major junctions | ||||
| South end: | I-75/SR 93/Hamilton CR 143 west of Jennings | |||
| North end: | US 41/SR 25/Hamilton CR 141 in Jennings | |||
| Highway system | ||||
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Florida State and County Roads
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State Road 143 is a north–south route in Hamilton County, running from I-75 southwest of Jennings to US 41 in Jennings.
South of I-75, County Road 143 continues to SR 6 at Blue Springs.
At its northern terminus with US 41, SR 143 connects with County Road 141, which goes north to the Georgia border, becoming Georgia State Route 135.